Rational physical activity is a fundamental factor in maintaining the physical health of young people. Studies by domestic researchers indicate a general decline in the level of physical activity among students under conditions of distance learning and the influence of stress-inducing factors. However, the choice of a future profession can significantly influence lifestyle and awareness of the need for regular physical activity. The aim of the study was to determine the volume and structure of weekly physical activity among first-year students majoring in “Therapy and Rehabilitation.” Methods: The short form of the International Physical Activity Questionnaire (IPAQ) was used to assess physical activity. The study included 88 first-year students at the Ivan Boberskyi Lviv State University of Physical Culture (54 females and 34 males, aged 17–23 years). Weekly energy expenditure for walking, moderate-intensity physical activity, and vigorous-intensity physical activity was determined in MET-min/week and kcal/week. 
Results: The students’ overall weekly level of physical activity was high, with an average energy expenditure of 7,467 MET-min/week (8,213.70 kcal/week). Walking dominated the activity profile (3,267 MET-min/week, with 72% of respondents engaging in it daily) along with high-intensity physical activity (3,840 MET-min/week, practiced 3–7 days a week by about 70% of individuals). In contrast, a significant deficit in moderate-intensity physical activity was identified: only 3% of students engaged in it daily, while 30% of respondents completely ignored this type of activity. 
Conclusion: The indicators of the total weekly energy expenditure among first-year students majoring in “Therapy and Rehabilitation” are high, which, in our opinion, is due to the specific nature of the chosen profession and the university. At the same time, a pronounced structural imbalance was observed due to a lack of moderate-intensity physical activity, highlighting the need to optimize and rationally plan students’ physical activity regimens to preserve their physical health.